| Date | Location | Result | |
| 11/19/22 | Martin, Tenn. | Tennessee State 3, Southeast Missouri 2 (25-21,16-25,22-25,25-22,15-10) | Box score |
| 11/18/22 | Martin, Tenn. | Southeast Missouri 3, UT Martin 2 (13-25,25-19,22-25,25-22,15-11) | Box score |
| 11/17/22 | Martin, Tenn. | Southeast Missouri 3, Eastern Illinois 2 (25-23,27-25,17-25,26-28,15-9) | Box score |
| 11/12/22 | Morehead, KY | Southeast Missouri 3, Morehead St. 0 (27-25,25-19,25-17) | Box score |
| 11/11/22 | Morehead, KY | Morehead St. 3, Southeast Missouri 2 (25-21,25-22,20-25,19-25,15-8) | Box score |
| 11/05/22 | Cape Girardeau, MO | Southeast Missouri 3, SIUE 1 (28-26,23-25,25-19,25-13) | Box score |
| 11/04/22 | Cape Girardeau, MO | Southeast Missouri 3, SIUE 1 (25-27,25-22,25-20,25-23) | Box score |
| 10/28/22 | Saint Charles, Mo. | Southeast Missouri 3, Lindenwood 2 (11-25,27-25,14-25,25-18,15-13) | Box score |
| 10/27/22 | Saint Charles, Mo. | Lindenwood 3, Southeast Missouri 2 (25-23,25-22,21-25,14-25,15-13) | Box score |
| 10/22/22 | Cape Girardeau, MO | Tennessee Tech 3, Southeast Missouri 1 (25-18,16-25,25-23,25-20) | Box score |
| 10/21/22 | Cape Girardeau, MO | Tennessee Tech 3, Southeast Missouri 1 (20-25,30-28,25-19,25-19) | Box score |
| 10/18/22 | Little Rock, AR | Little Rock 3, Southeast Missouri 2 (22-25,20-25,25-20,25-21,15-12) | Box score |
| 10/15/22 | Evansville, IND. | Southeast Missouri 3, Southern Indiana 1 (25-20,23-25,25-22,25-11) | Box score |
| 10/14/22 | Evansville, IND. | Southeast Missouri 3, Southern Indiana 0 (25-21,25-18,25-22) | Box score |
| 10/10/22 | Cape Girardeau, Mo. | Southeast Missouri 3, Little Rock 0 (25-17,25-23,25-18) | Box score |
| 10/08/22 | Cape Girardeau, Mo. | Eastern Illinois 3, Southeast Missouri 0 (25-20,25-17,25-20) | Box score |
| 10/07/22 | Cape Girardeau, Mo. | Eastern Illinois 3, Southeast Missouri 0 (25-23,25-19,26-24) | Box score |
| 10/01/22 | Martin, Tenn. | Southeast Missouri 3, UT Martin 0 (26-24,25-19,25-21) | Box score |
| 09/30/22 | Martin, Tenn. | UT Martin 3, Southeast Missouri 1 (25-19,30-28,17-25,25-19) | Box score |
| 09/24/22 | Cape Girardeau, Mo. | Southeast Missouri 3, Tennessee State 2 (25-23,21-25,23-25,25-17,15-8) | Box score |
| 09/23/22 | Cape Girardeau, Mo. | Southeast Missouri 3, Tennessee State 0 (26-24,25-22,25-22) | Box score |
| 09/17/22 | Carbondale, Ill. | Southeast Missouri 3, Alabama A&M 0 (25-15,25-11,25-23) | Box score |
| 09/16/22 | Carbondale, Ill. | Southern Ill. 3, Southeast Missouri 1 (25-18,25-20,22-25,25-19) | Box score |
| 09/16/22 | Carbondale, Ill. | Bellarmine 3, Southeast Missouri 1 (15-25,25-21,25-23,25-15) | Box score |
| 09/10/22 | Cedar Falls, Iowa | Southeast Missouri 3, Western Michigan 1 (25-22,21-25,25-23,25-18) | Box score |
| 09/10/22 | Cedar Falls, Iowa | UNI 3, Southeast Missouri 0 (25-14,25-20,26-24) | Box score |
| 09/09/22 | Cedar Falls, Iowa | Grand Canyon 3, Southeast Missouri 2 (18-25,25-19,23-25,25-21,15-8) | Box score |
| 09/03/22 | Normal, Ill. | Illinois State 3, Southeast Missouri 0 (25-18,27-25,25-16) | Box score |
| 09/02/22 | Normal, Ill. | Southeast Missouri 3, Oral Roberts 2 (25-20,22-25,25-12,12-25,15-9) | Box score |
| 09/02/22 | Normal, Ill. | Green Bay 3, Southeast Missouri 0 (25-19,25-23,25-15) | Box score |
| 08/27/22 | Cape Girardeau, Mo. | Southeast Missouri 3, Jackson State 1 (25-18,25-16,23-25,25-22) | Box score |
| 08/26/22 | Cape Girardeau, Mo. | North Dakota State 3, Southeast Missouri 2 (17-25,25-19,25-21,21-25,15-10) | Box score |
| 08/26/22 | Cape Girardeau, Mo. | Southeast Missouri 3, Arkansas-Pine Bluff 0 (25-12,25-19,25-15) | Box score |