| Date | Location | Result | |
| 05-27-10 | Jackson, Tenn. | Murray State 13, Southeast Missouri 9 | Box score |
| 05-26-10 | Jackson, Tenn. | Eastern Illinois 10, Southeast Missouri 5 | Box score |
| 05-22-10 | Charleston, Ill. | Southeast Missouri 10, Eastern Illinois 0 | Box score |
| 05-21-10 | Charleston, Ill. | Eastern Illinois 8, Southeast Missouri 5 | Box score |
| 05-21-10 | Charleston, Ill. | Eastern Illinois 7, Southeast Missouri 5 | Box score |
| 05-16-10 | Cape Girardeau, Mo. | Southeast Missouri 10, Austin Peay 3 | Box score |
| 05-15-10 | Cape Girardeau, Mo. | Southeast Missouri 2, Austin Peay 1 | Box score |
| 05-15-10 | Cape Girardeau, Mo. | Austin Peay 8, Southeast Missouri 4 | Box score |
| 05-09-10 | Lincoln, Neb. | Nebraska 10, Southeast Missouri 3 | Box score |
| 05-08-10 | Lincoln, Neb. | Nebraska 20, Southeast Missouri 6 | Box score |
| 05-07-10 | Lincoln, Neb. | Nebraska 6, Southeast Missouri 2 | Box score |
| 05-05-10 | Cape Girardeau, Mo. | Southeast Missouri 16, Mid-Continent 12 | Box score |
| 05-02-10 | Cape Girardeau, Mo. | Murray State 13, Southeast Missouri 9 | Box score |
| 05-02-10 | Cape Girardeau, Mo. | Murray State 5, Southeast Missouri 3 | Box score |
| 04-28-10 | Conway, Ark. | Southeast Missouri 13, Central Arkansas 11 | Box score |
| 04-27-10 | Conway, Ark. | Central Arkansas 8, Southeast Missouri 7 | Box score |
| 04-25-10 | Jacksonville, Ala. | Southeast Missouri 6, Jacksonville State 5 | Box score |
| 04-25-10 | Jacksonville, Ala. | Southeast Missouri 10, Jacksonville State 5 | Box score |
| 04-21-10 | Cape Girardeau, Mo. | Southeast Missouri 10, Harris-Stowe 2 | Box score |
| 04-20-10 | Carbondale, Ill | Southeast Missouri 13, Southern Illinois 1 | Box score |
| 04-18-10 | Martin, Tenn. | Southeast Missouri 15, UT Martin 1 | Box score |
| 04-17-10 | Martin, Tenn. | UT Martin 6, Southeast Missouri 3 | Box score |
| 04-17-10 | Martin, Tenn. | UT Martin 12, Southeast Missouri 4 | Box score |
| 04-14-10 | Jonesboro, Ark. | Arkansas State 9, Southeast Missouri 6 | Box score |
| 04-11-10 | Cape Girardeau, Mo. | Tennessee Tech 12, Southeast Missouri 8 | Box score |
| 04-10-10 | Cape Girardeau, Mo. | Southeast Missouri 4, Tennessee Tech 3 | Box score |
| 04-10-10 | Cape Girardeau, Mo. | Southeast Missouri 11, Tennessee Tech 9 | Box score |
| 04-06-10 | Cape Girardeau, Mo. | Southern Illinois 16, Southeast Missouri 11 | Box score |
| 04-03-10 | Cape Girardeau, Mo. | Southeast Missouri 8, Eastern Kentucky 7 | Box score |
| 04-02-10 | Cape Girardeau, Mo. | Southeast Missouri 7, Eastern Kentucky 4 | Box score |
| 04-02-10 | Cape Girardeau, Mo. | Southeast Missouri 17, Eastern Kentucky 9 | Box score |
| 03-28-10 | Morehead, Ky. | Southeast Missouri 15, Morehead State 7 | Box score |
| 03-27-10 | Morehead, Ky. | Morehead State 12, Southeast Missouri 11 | Box score |
| 03-27-10 | Morehead, Ky. | Southeast Missouri 23, Morehead State 10 | Box score |
| 03-24-10 | Cape Girardeau, Mo. | Southeast Missouri 6, Arkansas State 4 | Box score |
| 03-23-10 | Cape Girardeau, Mo. | Southeast Missouri 8, Saint Louis 4 | Box score |
| 03-20-10 | Cape Girardeau, Mo. | Southeast Missouri 8, Valparaiso 7 | Box score |
| 03-19-10 | Cape Girardeau, Mo. | Southeast Missouri 5, Valparaiso 3 | Box score |
| 03-19-10 | Cape Girardeau, Mo. | Southeast Missouri 17, Valparaiso 4 | Box score |
| 03-16-10 | Cape Girardeau, Mo. | Southeast Missouri 13, Freed-Hardeman 1 | Box score |
| 03-14-10 | Cape Girardeau, Mo. | Southeast Missouri 14, North Dakota 4 | Box score |
| 03-13-10 | Cape Girardeau, Mo. | North Dakota 6, Southeast Missouri 5 | Box score |
| 03-13-10 | Cape Girardeau, Mo. | Southeast Missouri 15, North Dakota 4 | Box score |
| 03-10-10 | Cape Girardeau, Mo. | Southeast Missouri 12, Missouri State 11 | Box score |
| 03-07-10 | Starkville, Miss. | Michigan State 9, Southeast Missouri 0 | Box score |
| 03-06-10 | Starkville, Miss. | Mississippi State 3, Southeast Missouri 2 | Box score |
| 03-05-10 | Starkville, Miss. | Mississippi State 10, Southeast Missouri 7 | Box score |
| 03-05-10 | Starkville, Miss. | Michigan State 8, Southeast Missouri 7 | Box score |
| 03-02-10 | St. Louis, Mo. | Saint Louis 10, Southeast Missouri 6 | Box score |
| 02-28-10 | Cape Girardeau, Mo. | Southeast Missouri 6, IPFW 5 | Box score |
| 02-27-10 | Cape Girardeau, Mo. | Southeast Missouri 3, IPFW 2 | Box score |
| 02-26-10 | Cape Girardeau, Mo. | Southeast Missouri 5, IPFW 0 | Box score |
| 02-21-10 | Auburn, Ala. | Auburn 6, Southeast Missouri 1 | Box score |
| 02-20-10 | Auburn, Ala. | Auburn 9, Southeast Missouri 8 | Box score |
| 02-19-10 | Auburn, Ala. | Southeast Missouri 13, Auburn 8 | Box score |