| Date | Location | Result | |
| 03-14-23 | UD Arena -- Dayton, Ohio | A&M-Corpus Christi 75, Southeast Mo. St. 71 | Box score |
| 03-04-23 | Ford Center -- Evansville, Ind. | Southeast Mo. St. 89, Tennessee Tech 82 (OT) | Box score |
| 03-03-23 | Ford Center -- Evansville, Ind. | Southeast Mo. St. 65, Morehead St. 58 | Box score |
| 03-02-23 | Ford Center -- Evansville, Ind. | Southeast Mo. St. 91, Tennessee St. 83 | Box score |
| 03-01-23 | Ford Center -- Evansville, Ind. | Southeast Mo. St. 84, Lindenwood 65 | Box score |
| 02-25-23 | First Comm. Arena -- Edwardsville, Ill. | SIUE 93, Southeast Mo. St. 78 | Box score |
| 02-23-23 | Hyland Arena -- St. Charles, Mo. | Lindenwood 105, Southeast Mo. St. 102 (2OT) | Box score |
| 02-18-23 | Show Me Center -- Cape Girardeau, Mo. | Southeast Mo. St. 85, Southern Ind. 80 | Box score |
| 02-16-23 | Show Me Center -- Cape Girardeau, Mo. | Southeast Mo. St. 78, Eastern Ill. 64 | Box score |
| 02-11-23 | Show Me Center -- Cape Girardeau, Mo. | Morehead St. 65, Southeast Mo. St. 59 | Box score |
| 02-09-23 | Gentry Center -- Nashville, Tenn. | Tennessee St. 85, Southeast Mo. St. 65 | Box score |
| 02-04-23 | Eblen Center -- Cookeville, Tenn. | Tennessee Tech 82, Southeast Mo. St. 80 | Box score |
| 02-02-23 | Show Me Center -- Cape Girardeau, Mo. | Southeast Mo. St. 99, Little Rock 98 | Box score |
| 01-28-23 | Lantz Arena -- Charleston, Ill. | Southeast Mo. St. 79, Eastern Ill. 68 | Box score |
| 01-26-23 | Show Me Center -- Cape Girardeau, Mo. | Southeast Mo. St. 92, Tennessee St. 75 | Box score |
| 01-21-23 | Show Me Center -- Cape Girardeau, Mo. | Southeast Mo. St. 84, Tennessee Tech 77 (2OT) | Box score |
| 01-19-23 | Show Me Center -- Cape Girardeau, Mo. | UT Martin 80, Southeast Mo. St. 60 | Box score |
| 01-14-23 | Johnson Arena -- Morehead, Ky. | Southeast Mo. St. 91, Morehead St. 86 | Box score |
| 01-12-23 | Show Me Center -- Cape Girardeau, Mo. | Southeast Mo. St. 94, Lindenwood 71 | Box score |
| 01-07-23 | Jack Stephens Center -- Little Rock, Ark | Southeast Mo. St. 74, Little Rock 68 | Box score |
| 01-05-23 | Elam Center -- Martin, Tenn. | UT Martin 87, Southeast Mo. St. 82 | Box score |
| 12-31-22 | Show Me Center -- Cape Girardeau, Mo. | Southeast Mo. St. 82, SIUE 73 | Box score |
| 12-29-22 | Screaming Eagles Arena -- Evansville, IN | Southern Ind. 86, Southeast Mo. St. 81 | Box score |
| 12-21-22 | Show Me Center -- Cape Girardeau, Mo. | Southern Ill. 70, Southeast Mo. St. 68 | Box score |
| 12-17-22 | Carver-Hawkeye Arena -- Iowa City, Iowa | Iowa 106, Southeast Mo. St. 75 | Box score |
| 12-14-22 | First Nat. Bank Arena -- Jonesboro, Ark. | Arkansas St. 68, Southeast Mo. St. 61 | Box score |
| 12-07-22 | Show Me Center -- Cape Girardeau, Mo. | Purdue Fort Wayne 89, Southeast Mo. St. 68 | Box score |
| 12-04-22 | Mizzou Arena -- Columbia, Mo. | Missouri 96, Southeast Mo. St. 89 | Box score |
| 11-28-22 | Klotsche Center - Milwaukee, Wis. | Milwaukee 84, Southeast Mo. St. 68 | Box score |
| 11-27-22 | Klotsche Center -- Milwaukee, Wis. | UC Davis 73, Southeast Mo. St. 71 | Box score |
| 11-26-22 | Klotsche Center -- Milwaukee, Wis. | Southeast Mo. St. 63, Boston U. 52 | Box score |
| 11-22-22 | Show Me Center -- Cape Girardeau, Mo. | Southeast Mo. St. 87, William Woods 49 | Box score |
| 11-19-22 | Carver Arena -- Peoria, Ill. | Bradley 73, Southeast Mo. St. 60 | Box score |
| 11-16-22 | Ford Cener -- Evansville, Ind. | Southeast Mo. St. 67, Evansville 61 | Box score |
| 11-12-22 | Show Me Center -- Cape Girardeau, Mo. | Southeast Mo. St. 83, Lyon 46 | Box score |
| 11-07-22 | Yuengling Center -- Tampa, Fla. | Southeast Mo. St. 64, South Fla. 61 | Box score |