| Date | Location | Result | |
| 03/03/23 | Evansville, IN | Little Rock 49, Southeast Mo. St. 35 | Box score |
| 03/02/23 | Evansville, IN | Southeast Mo. St. 77, Morehead St. 38 | Box score |
| 02/25/23 | Edwardsville, IL | Southeast Mo. St. 88, SIUE 72 | Box score |
| 02/23/23 | Saint Charles, MO | Southeast Mo. St. 67, Lindenwood 62 | Box score |
| 02/18/23 | Cape Girardeau, MO | Southeast Mo. St. 63, Southern Ind. 59 | Box score |
| 02/16/23 | Cape Girardeau, MO | Southeast Mo. St. 62, Eastern Ill. 57 | Box score |
| 02/11/23 | Cape Girardeau, MO | Southeast Mo. St. 69, Morehead St. 55 | Box score |
| 02/09/23 | Nashville, TN | Southeast Mo. St. 90, Tennessee St. 86 (OT) | Box score |
| 02/04/23 | Cookeville, TN | Tennessee Tech 71, Southeast Mo. St. 65 | Box score |
| 02/02/23 | Cape Girardeau, MO | Little Rock 58, Southeast Mo. St. 39 | Box score |
| 01/28/23 | Charleston, IL | Eastern Ill. 63, Southeast Mo. St. 57 | Box score |
| 01/26/23 | Cape Girardeau, MO | Southeast Mo. St. 77, Tennessee St. 59 | Box score |
| 01/21/23 | Cape Girardeau, MO | Tennessee Tech 76, Southeast Mo. St. 72 | Box score |
| 01/19/23 | Cape Girardeau, MO | Southeast Mo. St. 56, UT Martin 54 | Box score |
| 01/14/23 | Morehead, KY | Southeast Mo. St. 87, Morehead St. 77 | Box score |
| 01/12/23 | Cape Girardeau, MO | Southeast Mo. St. 68, Lindenwood 45 | Box score |
| 01/07/23 | Little Rock, AR | Little Rock 65, Southeast Mo. St. 45 | Box score |
| 01/05/23 | Martin, TN | UT Martin 77, Southeast Mo. St. 58 | Box score |
| 12/31/22 | Cape Girardeau, MO | SIUE 76, Southeast Mo. St. 61 | Box score |
| 12/29/22 | Evansville, IN | Southern Ind. 68, Southeast Mo. St. 54 | Box score |
| 12/20/22 | Cape Girardeau, MO | Southeast Mo. St. 56, UIC 55 | Box score |
| 12/18/22 | Evansville, IN | Evansville 64, Southeast Mo. St. 53 | Box score |
| 12/07/22 | Cape Girardeau, MO | Southeast Mo. St. 63, Western Ill. 55 | Box score |
| 12/04/22 | Lawrence, KS | Kansas 88, Southeast Mo. St. 51 | Box score |
| 12/01/22 | Cape Girardeau, MO | Southeast Mo. St. 63, Rust 60 | Box score |
| 11/27/22 | Orlando, FL | UCF 67, Southeast Mo. St. 41 | Box score |
| 11/26/22 | Orlando, FL | Rhode Island 66, Southeast Mo. St. 49 | Box score |
| 11/18/22 | Cape Girardeau, MO | Southeast Mo. St. 76, LeMoyne-Owen 45 | Box score |
| 11/13/22 | Columbia, MO | Missouri 62, Southeast Mo. St. 50 | Box score |
| 11/10/22 | Oxford, MS | Ole Miss 83, Southeast Mo. St. 57 | Box score |
| 11/07/22 | Cape Girardeau, MO | Southeast Mo. St. 60, St. Louis Pharmacy 48 | Box score |