| Date | Location | Result | |
| 02/28/18 | Evansville, Ind. (Ford Center) | UT Martin 63, Southeast Missouri 60 | Box score |
| 2/24/18 | Cape Girardeau, Mo. (Show Me Center) | UT Martin 69, Southeast Missouri 68 | Box score |
| 02/22/18 | Richmond, Ky. (McBrayer Arena) | Southeast Missouri 66, Eastern Kentucky University 52 | Box score |
| 2/17/18 | Cape Girardeau, Mo. | Southeast Missouri 72, SIUE 62 | Box score |
| 2/14/18 | Cape Girardeau, Mo. (Show Me Center) | Southeast Missouri 51, Eastern Illinois 48 | Box score |
| 2/10/18 | Elam Center - Martin, Tenn. | UT Martin 72, Southeast Missouri 65 | Box score |
| 2/8/18 | Morehead, Ky. / Johnson Arena | Morehead State 60, Southeast Missouri 58 (OT) | Box score |
| 2/3/18 | Cape Girardeau, Mo. (Show Me Center) | Austin Peay 61, Southeast Missouri 50 | Box score |
| 2/1/18 | Cape Girardeau, Mo. (Show Me Center) | Southeast Missouri 80, Murray St. 70 | Box score |
| 1/27/18 | Jacksonville, Ala. (Pete Mathews Col.) | Jacksonville State 55, Southeast Missouri 48 | Box score |
| 01/25/18 | Cookeville, Tenn. (Eblen Center) | Southeast Missouri 70, Tennessee Tech 66 | Box score |
| 1/20/18 | Charleston, Ill. | Southeast Missouri 77, Eastern Illinois 54 | Box score |
| 01/17/18 | Edwardsville, Ill./Vadalabene Center | SIUE 65, Southeast Missouri 57 | Box score |
| 1/13/18 | Cape Girardeau, Mo. (Show Me Center) | Southeast Missouri 69, Eastern Kentucky 55 | Box score |
| 1/11/18 | Cape Girardeau, Mo. (Show Me Center) | Morehead State 59, Southeast Missouri 56 | Box score |
| 1/6/18 | Clarksville, Tenn. (Dunn Center) | Austin Peay 66, Southeast Missouri 65 | Box score |
| 01/04/18 | Murray, Ky. (CFSB Center) | Southeast Mo. St. 85, Murray St. 74 | Box score |
| 12/30/17 | Cape Girardeau, Mo. (Show Me Center) | Southeast Missouri 71, Tennessee State 66 | Box score |
| 12/28/17 | Show Me Center -- Cape Girardeau, Mo. | Belmont 67, Southeast Missouri 57 | Box score |
| 12/19/17 | Show Me Center -- Cape Girardeau, Mo. | Southeast Missouri 74, Evansville 65 | Box score |
| 12/10/17 | Lawrence, Kan. (Allen Fieldhouse) | Kansas 51, Southeast Missouri 50 | Box score |
| 12/7/17 | Muncie, Ind. (Worthen Arena) | Ball State 69, Southeast Missouri S 56 | Box score |
| 12/5/17 | Western Hall in Macomb, Ill. | Western Illinois 87, SEMO 59 | Box score |
| 11/30/17 | Saint Ursula Academy (Cincinnati, Ohio) | Cincinnati 65, Southeast Missouri 52 | Box score |
| 11/25/17 | Show Me Center -- Cape Girardeau, Mo. | Southeast Missouri 57, Bradley 53 | Box score |
| 11/24/17 | Show Me Center -- Cape Girardeau, Mo. | Southeast Missouri 72, Evangel 60 | Box score |
| 11/22/17 | Show Me Center | Southern Illinois 79, Southeast Missouri 74 (OT) | Box score |
| 11/18/17 | EagleBank Arena (Fairfax, Va.) | George Mason 57, Southeast Missouri S 38 | Box score |
| 11/17/17 | EagleBank Arena (Fairfax, Va.) | Southeast Missouri S 82, Saint Francis (Pa.) 50 | Box score |
| 11/14/17 | Show Me Center | Southeast Missouri 69, Missouri Valley College 34 | Box score |
| 11/10/17 | KFC Yum! Center, Louisville, KY | LOUISVILLE 80, SEMO 40 | Box score |