| Date | Location | Result | |
| 12-02-25 | Show Me Center -- Cape Girardeau, Mo. | Southeast Mo. St. 88, St. Mary-Woods 57 | Box score |
| 11-29-25 | Show Me Center -- Cape Girardeau, Mo. | Lipscomb 88, Southeast Mo. St. 77 | Box score |
| 11-26-25 | Rolle Activity Center -- Flagstaff, Ariz | Northern Ariz. 79, Southeast Mo. St. 72 | Box score |
| 11-25-25 | Rolle Activity Center -- Flagstaff, Ariz | Southeast Mo. St. 84, Cal Poly 68 | Box score |
| 11-18-25 | Carver-Hawkeye Arena -- Iowa City, Iowa | Iowa 99, Southeast Mo. St. 70 | Box score |
| 11-15-25 | Show Me Center -- Cape Girardeau, Mo. | St. Thomas (MN) 84, Southeast Mo. St. 72 | Box score |
| 11-12-25 | Show Me Center -- Cape Girardeau, Mo. | Southeast Mo. St. 87, Webster 41 | Box score |
| 11-07-25 | Mizzou Arena -- Columbia, Mo. | Missouri 89, Southeast Mo. St. 84 | Box score |
| 11-03-25 | Chaifetz Arena -- St. Louis, Mo. | Saint Louis 92, Southeast Mo. St. 67 | Box score |