| Date | Location | Result | |
| 02-27-01 | Dunn Center -- Clarksville, Tenn. | Austin Peay 72, Southeast Missouri 70 (OT) | Box score |
| 02-24-01 | Show Me Center -- Cape Girardeau, Mo. | Southeast Missouri 63, Morehead State 61 | Box score |
| 02-22-01 | Show Me Center -- Cape Girardeau, Mo. | Southeast Missouri 81, Eastern Kentucky 70 | Box score |
| 02-17-01 | Show Me Center -- Cape Girardeau, Mo. | Southeast Missouri 75, Eastern Illinois 73 | Box score |
| 02-14-01 | Show Me Center -- Cape Girardeau, Mo. | Southeast Missouri 83, Morris Brown College 50 | Box score |
| 02-10-01 | Elam Center -- Martin, Tenn. | Southeast Missouri 81, UT Martin 73 | Box score |
| 02-08-01 | Reg. Special Events Ctr. -- Murray, Ky. | Murray State 65, Southeast Missouri 54 | Box score |
| 02-06-01 | Eblen Center -- Cookeville, Tenn. | Tennessee Tech 79, Southeast Missouri 69 | Box score |
| 02-03-01 | Show Me Center -- Cape Girardeau, Mo. | Tennessee State 96, Southeast Missouri 94 | Box score |
| 02-01-01 | Show Me Center -- Cape Girardeau, Mo. | Austin Peay 77, Southeast Missouri 72 | Box score |
| 01-29-01 | McBrayer Arena -- Richmond, Ky. | Southeast Missouri 65, Eastern Kentucky 59 | Box score |
| 01-27-01 | Johnson Arena -- Morehead, Ky. | Southeast Missouri 74, Morehead State 71 | Box score |
| 01-22-01 | Lewis Arena -- Atlanta, Ga. | Southeast Missouri 82, Morris Brown College 63 | Box score |
| 01-20-01 | Lantz Arena -- Charleston, Ill. | Eastern Illinois 83, Southeast Missouri 71 | Box score |
| 01-13-01 | Show Me Center -- Cape Girardeau, Mo. | Southeast Missouri 60, UT Martin 49 | Box score |
| 01-11-01 | Show Me Center -- Cape Girardeau, Mo. | Murray State 60, Southeast Missouri 58 | Box score |
| 01-06-01 | Dunn Center -- Clarksville, Tenn. | Austin Peay 88, Southeast Missouri 60 | Box score |
| 01-04-01 | Gentry Center -- Nashville, Tenn. | Southeast Missouri 88, Tennessee State 57 | Box score |
| 12-28-00 | Haskins Center -- El Paso, Texas | Southeast Missouri 72, Jackson State 63 | Box score |
| 12-27-00 | Haskins Center -- El Paso, Texas | Houston 69, Southeast Missouri 64 | Box score |
| 12-20-00 | Show Me Center -- Cape Girardeau, Mo. | Southeast Missouri 81, Campbell 54 | Box score |
| 12-16-00 | Show Me Center -- Cape Girardeau, Mo. | Southeast Missouri 73, Missouri State 71 | Box score |
| 12-09-00 | Show Me Center -- Cape Girardeau, Mo. | Tennessee Tech 70, Southeast Missouri 68 | Box score |
| 12-05-00 | Show Me Center -- Cape Girardeau, Mo. | Southeast Missouri 87, Southern Illinois 84 | Box score |
| 11-29-00 | Harrison Complex -- Itta Bena, Miss. | Mississippi Valley State 83, Southeast Missouri 77 | Box score |
| 11-26-00 | Municipal Auditorium -- Kansas City, Mo. | Southeast Missouri 72, Cleveland State 71 | Box score |
| 11-25-00 | Municipal Auditorium -- Kansas City, Mo. | Southeast Missouri 78, Robert Morris 53 | Box score |
| 11-24-00 | Municipal Auditorium -- Kansas City, Mo. | Toledo 59, Southeast Missouri 43 | Box score |
| 11-21-00 | Show Me Center -- Cape Girardeau, Mo. | Southeast Missouri 87, Missouri S&T 63 | Box score |
| 11-17-00 | Show Me Center -- Cape Girardeau, Mo. | Southeast Missouri 70, Truman State 59 | Box score |