| Date | Location | Result | |
| 04-11-21 | Nashville, Tenn. | Southeast Missouri 46, TSU 23 | Box score |
| 04-03-21 | Martin, Tenn. | Southeast Missouri 21, UT Martin 16 | Box score |
| 03-28-21 | Cape Girardeau, Mo. | Southeast Missouri 24, Tennessee Tech 21 | Box score |
| 03-21-21 | Jacksonville, Ala. | Jacksonville State 21, Southeast Missouri 3 | Box score |
| 03-14-21 | Cape Girardeau, Mo. | Austin Peay 49, Southeast Missouri 42 | Box score |
| 03-07-21 | Cape Girardeau, Mo. | Murray State 24, Southeast Missouri 21 | Box score |
| 02-28-21 | Charleston, Ill. | Southeast Missouri 47, Eastern Illinois 7 | Box score |
| 10-30-20 | Carbondale, Ill. | Southern Illinois 20, Southeast Missouri 17 | Box score |