| Date | Location | Result | |
| 11-18-17 | Cape Girardeau, Mo. | Southeast Missouri 21, Murray State 10 | Box score |
| 11-11-17 | Nashville, Tenn. | Tennessee State 23, Southeast Missouri 20 | Box score |
| 11-04-17 | Cape Girardeau, Mo. | UT Martin 16, Southeast Missouri 14 | Box score |
| 10-28-17 | Jacksonville, Ala. | Jacksonville State 23, Southeast Missouri 7 | Box score |
| 10-21-17 | Clarksville, Tenn. | Austin Peay 38, Southeast Missouri 31 | Box score |
| 10-14-17 | Cape Girardeau, Mo. | Southeast Missouri 31, Tennessee Tech 3 | Box score |
| 09-30-17 | Cape Girardeau, Mo. | Southeast Missouri 29, Eastern Kentucky 10 | Box score |
| 09-23-17 | Charleston, Ill. | Eastern Illinois 19, Southeast Missouri 16 | Box score |
| 09-16-17 | Cape Girardeau, Mo. | Southern Illinois 35, Southeast Missouri 17 | Box score |
| 09-09-17 | Dayton, Ohio | Dayton 25, Southeast Missouri 23 | Box score |
| 09-02-17 | Lawrence, Kan. | Kansas 38, Southeast Missouri 16 | Box score |