| Date | Location | Result | |
| 11-19-16 | Cape Girardeau, Mo. | Tennessee State 32, Southeast Missouri 31 | Box score |
| 11-12-16 | Martin, Tenn. | UT Martin 24, Southeast Missouri 10 | Box score |
| 11-05-16 | Cape Girardeau, Mo. | Jacksonville State 17, Southeast Missouri 10 | Box score |
| 10-29-16 | Cape Girardeau, Mo. | Southeast Missouri 41, Austin Peay 21 | Box score |
| 10-22-16 | Cookeville, Tenn. | Tennessee Tech 21, Southeast Missouri 20 | Box score |
| 10-08-16 | Richmond, Ky. | Eastern Kentucky 31, Southeast Missouri 16 | Box score |
| 10-01-16 | Cape Girardeau, Mo. | Southeast Missouri 21, Eastern Illinois 14 | Box score |
| 09-24-16 | Murray, Ky. | Southeast Missouri 17, Murray State 16 | Box score |
| 09-17-16 | Cape Girardeau, Mo. | Indiana State 27, Southeast Missouri 24 | Box score |
| 09-10-16 | Carbondale, Ill. | SIU 30, Southeast Missouri 22 | Box score |
| 09-03-16 | Memphis, Tenn. | MEMPHIS 35, Southeast Missouri 17 | Box score |